No. S2 nor EZD2 (nor EZkeys, or EZmix) have a resizable GUI. This question was answered on post #2 if this thread.
I don't use Windows 10 personally so I don't know what issues you are having specifically with that OS. I use a Win7 machine and a 27" Touchscreen monitor at a 1920X1080 resolution (my GUI looks like the attached pic below). The GUI is plenty large on my system (and fingers). Again, please use the link in the FAQ to contact Toontrack Support directly.
At the very top of the FAQ page:
...'Please search for your question, the contact support button can be found at the bottom of each FAQ answer'.
So, please use the Contact Support button to contact Toontrack directly to find a more direct answer to your question.
